منابع مشابه
5-HTTLPR and COMTval158met genotype gate amygdala reactivity and habituation.
Amygdala reactivity is a heritable trait, potentiated in affective disorders and associated with both the 5-HTTLPR and the COMTval158met polymorphism. Fifty-four healthy volunteers selected a priori based on gender and 5-HTTLPR/rs25531 and COMTval158met genotypes performed a passive viewing task of angry facial expressions using fMRI. Amygdala reactivity and habituation were investigated using ...
متن کاملThreat-related amygdala functional connectivity is associated with 5-HTTLPR genotype and neuroticism.
Communication between the amygdala and other brain regions critically regulates sensitivity to threat, which has been associated with risk for mood and affective disorders. The extent to which these neural pathways are genetically determined or correlate with risk-related personality measures is not fully understood. Using functional magnetic resonance imaging, we evaluated independent and inte...
متن کامل5-HTTLPR, anxiety and gender interaction moderates right amygdala volume in healthy subjects.
Genetic variants within the serotonin transporter gene (5-HTTLPR) impact the neurobiology and risk for anxiety-related behaviours. There are also gender differences in the prevalence of anxiety-related behaviours. Although numerous studies have investigated the influence of 5-HTTLPR genotype on the neural systems involved in emotional regulation, none have investigated how these effects are mod...
متن کاملWar exposure, 5-HTTLPR genotype and lifetime risk of depression.
BACKGROUND In 1962 approximately 1.5 million French people living in Algeria were repatriated to France in very poor and often life-threatening conditions. These people constitute a cohort for the study of the long-term impact of gene-environment interaction on depression. AIMS To examine the interaction between a highly stressful life event and subsequent depression, and its modulation by a ...
متن کاملSerotonin Transporter Genotype (5-HTTLPR) Predicts Utilitarian Moral Judgments
BACKGROUND The psychological and neurobiological processes underlying moral judgment have been the focus of extensive recent research. Here we show that serotonin transporter (5-HTTLPR) genotype predicts responses to moral dilemmas featuring foreseen harm to an innocent. METHODOLOGY/PRINCIPAL FINDINGS Participants in this study judged the acceptability of actions that would unintentionally or...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Archives of Psychiatry and Clinical Neuroscience
سال: 2009
ISSN: 0940-1334,1433-8491
DOI: 10.1007/s00406-008-0853-4